Free Shipping
on all orders
Delivery TimeShipping Method
1 - 5 business daysFREE Standard Delivery
2 business daysFedEx 2Day
1 business dayFedEx Overnight

Carriers

fedex shipping logoups shipping logousps shipping logo
 
LoginCreate an account
Change country

Thorne 5-MTHF

Visit the Thorne Store
Review Rating: 4.8 /5
(5 reviews)
 
 

Thorne 5-MTHF

Here's something most athletes don't know: nearly 60% of people have a genetic variation that makes it harder for their bodies to use regular folate effectively. If you're struggling with energy production, recovery, or just feeling "off" despite solid training and nutrition, this could be the missing piece.

The Methylation Connection

Folate is crucial for your body's methylation cycle—a series of biochemical reactions that impact everything from cellular energy production to neurotransmitter creation. When this cycle isn't working optimally, it affects heart health, brain function, fat metabolism, liver detoxification, and even bone health.

Thorne's 5-MTHF provides the active, methylated form of folate that your body can use immediately, without the extra metabolic work required to convert synthetic folic acid. This is especially critical if you have an MTHFR gene mutation, which affects how well your body processes folate and detoxes.

You May Need This

Your training demands optimal cellular energy production and neurotransmitter function. 5-MTHF supports the production of serotonin, dopamine, and epinephrine—brain chemicals that directly impact mood, focus, and stress response. Better methylation also means more efficient fat metabolism and cellular repair.

Thorne 5-MTHF Highlights:

  • Active Methylated Folate: Body-ready 5-MTHF form (1mg or 5mg doses) for maximum absorption
  • MTHFR Gene Support: Great for the 60% with genetic variations affecting folate processing
  • Neurotransmitter Production: Supports serotonin, dopamine, and other key brain chemicals
  • Cardiovascular & Brain Health: Maintains healthy homocysteine levels and methylation
  • Cellular Energy Support: Optimizes the biochemical processes that fuel performance
  • Small, Easy Capsules: Simple daily supplementation

How to Use Thorne 5-MTHF:

Take one capsule one to two times daily. The 1mg dose provides comprehensive support for methylation without overwhelming your system. The 5mg dose is a more concentrated options. Take in accordance as recommended by your health-care practitioner.

  • Gluten free

    Supplement Facts

    1 mg - 60 Servings
    Serving Size: 1 Capsule
    Serving Per Container: 60

    Amount Per Serving
    % Daily Value*
    Folate (1 mg as L-5-Methyltetrahydrofolate) 1.7mg DFE**

    * Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.
    ** Daily Value (DV) not established

    Ingredients for Thorne 5-MTHF (1 mg - 60 Servings): Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.

    Thorne 5-MTHF Reviews

    Thorne 5-MTHF Questions