Product Description
Athletes on plant-forward diets, or anyone with an MTHFR variant that makes standard folic acid harder to use, often need more from their B-vitamin routine than a generic multivitamin provides. Methyl Charge+ pairs four B vitamins in their active, methylated forms with TMG for that specific need.
Methyl Charge+ delivers methylated B12, active B6, riboflavin, and folate alongside TMG in one liposomal formula built to support your body's methylation cycle.
Vitamins in the Form Your Body Can Actually Use – Folate, B12, and B6 are all delivered in active or methylated forms here, which matters if you have an MTHFR variant or another reason standard folic acid and cyanocobalamin don't convert well for you.
A Boost for the Methylation Cycle – TMG is added specifically to support the methylation cycle these B vitamins feed into, rounding out the formula beyond what a standard multivitamin's B-vitamin panel usually covers.
Built to Pair With Your NAD+ Routine – Methylation and NAD+ production are closely linked processes, so this formula is designed to complement an NAD+ supplement rather than compete with it for the same nutritional pathway.
Methyl Charge+ delivers methylated B12 (methylcobalamin), active B6, riboflavin, and folate as calcium folinate, alongside TMG (trimethylglycine), all ingredients that feed directly into your body's methylation cycle. This cycle also supports glutathione production and processes tied to cellular energy and healthy aging, which is why some people pair this formula with an NAD+ supplement.
How to Use Methyl Charge+®
Dose: Take 2 pumps by mouth, held in your mouth 30 to 90 seconds before swallowing, on an empty stomach at least 10 minutes before meals. Repeat to desired dosage as directed by a healthcare professional. Use within 90 days of opening.
- Gluten free
- Vegan
Supplement Facts
50 Servings
Serving Size: 1 mL (2 Pumps)
Serving Per Container: 50
| Amount Per Serving | ||
|---|---|---|
| % Daily Value* | ||
| Riboflavin (as Riboflavin-5-Phosphate) 7mg | ** | |
| Vitamin B6 (as Pyridoxine HCl) 1mg | ** | |
| Folate (as Calcium Folinate) 850mcg DFE | ** | |
| Vitamin B12 (as Methylcobalamin) 500mcg | ** | |
| Trimethylglycine (betaine) 75mg | ** | |
* Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.
** Daily Value (DV) not established
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Quicksilver Scientific Methyl Charge+® FAQ's
Everything you need to know about Quicksilver Scientific Methyl Charge+®.



A liposomal methylation-support formula built from four key B vitamins (methyl B12, folate, B6, and riboflavin) plus TMG (trimethylglycine). Methylation is a behind-the-scenes process your body runs constantly for energy, detox, and cellular repair, and this keeps those wheels turning.
Your methylation cycle ties into energy production, detoxification, glutathione (your body's master antioxidant), and healthy aging. Supporting it with the right B vitamins helps those systems run smoothly, which is why it's popular for undermethylators and detox protocols.
It uses active, methylated forms like methyl B12 and folate (as calcium folinate) that your body can use directly, rather than forms it has to convert first. That matters for people whose genetics make that conversion less efficient.
Take 2 pumps by mouth, holding in your mouth 30 to 90 seconds before swallowing, on an empty stomach at least 10 minutes before meals. It has a cinnamon-forward taste, and it's potent, so start low if you're sensitive to B vitamins.
Yes. It's designed to pair well with NAD+ boosters since the NAD+ and methylation cycles are closely linked, and it fits into detox and healthy-aging routines. If you're on medications or have a health condition, check with your provider first.