Product Description
Most B-complex formulas stop at basic energy metabolism, but B vitamins also serve as direct cofactors in mitochondrial function and nerve signaling. One specific form of B12, adenosylcobalamin, has been linked in animal research to maintaining fast-twitch muscle fiber size and neuromuscular junction integrity as those systems age.
Pure Encapsulations Ultra B-Complex w/PQQ combines high-dose B vitamins with PQQ, alpha lipoic acid, and luteolin to support mitochondrial bioenergetics and nerve health.
Targets Nerve and Muscle Health – Adenosylcobalamin, one of two active B12 forms in this formula, has been linked in animal research to maintaining fast-twitch muscle fiber size and neuromuscular junction integrity, extending this formula's reach beyond typical B-complex energy claims.
PQQ Supports Mitochondrial Biogenesis – Beyond the B vitamins' role as coenzymes, PQQ supports the formation of new mitochondria and provides antioxidant activity through a separate pathway, a mechanism standard B-complex formulas don't cover.
Rounded Out With Alpha Lipoic Acid and Luteolin – These two antioxidants support mitochondrial energy utilization and nervous system antioxidant activity, adding coverage beyond what B vitamins and PQQ address alone.
B-complex vitamins act as metabolic coenzymes and methyl donors essential to basal mitochondrial function, and thiamin and niacin specifically support neuron cell longevity and impulse conduction. Folate (as Metafolin) and B6 serve as methylation cofactors in myelin and neurotransmitter synthesis, while adenosylcobalamin, the active B12 form used in mitochondria, has been linked in animal research to maintaining fast-twitch muscle fiber size and neuromuscular junction integrity with aging. PQQ adds B-vitamin-like antioxidant activity and supports mitochondrial biogenesis, and alpha lipoic acid and luteolin round out the formula with additional antioxidant support.
How to Use Pure Encapsulations Ultra B-Complex w/ PQQ
Dose: Take 1 capsule, 1 to 2 times daily, with meals.
This is a high-potency formula. Several B vitamins here run well above typical multivitamin amounts, so it's meant as a targeted mitochondrial and nerve-support product rather than a general daily multivitamin replacement.
If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
- Gluten free
- Vegan
- Nut free
Supplement Facts
60 Servings
Serving Size: 1 Capsule
Serving Per Container: 60
| Amount Per Serving | ||
|---|---|---|
| % Daily Value* | ||
| Thiamin (as thiamin HCl) 125mg | ** | |
| Riboflavin (vitamin B2 and 60% riboflavin 5' phosphate (activated B2)) 12.7mg | ** | |
| Niacin (as niacinamide and 8% inositol hexanicinate (no-flush niacin)) 108mg | ** | |
| Vitamin B6 (as pyridoxine HCl and 7% pyridoxal 5' phosphate (activated B6)) 96.7mg | ** | |
| Folate (as Metafolin®, L-5-MTHF) (400 mcg L-5-MTHF) 667mcg DFE | ** | |
| Vitamin B12 (as methylcobalamin and 50% adenosylcobalamin) 1000mcg | ** | |
| Biotin 400mcg | ** | |
| Pantothenic acid (as calcium pantothenate) (B5) 100mg | ** | |
| Alpha lipoic acid (thioctic acid) 100mg | ** | |
| Luteolin 20mg | ** | |
| BioPQQ® pyrroloquinoline quinone disodium salt 10mg | ** | |
* Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.
** Daily Value (DV) not established
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Pure Encapsulations Ultra B-Complex w/ PQQ FAQ's
Everything you need to know about Pure Encapsulations Ultra B-Complex w/ PQQ.



Most B-complex formulas stop at basic energy metabolism. This one adds PQQ to support the formation of new mitochondria through a separate pathway, plus alpha lipoic acid and luteolin for additional antioxidant coverage — mechanisms standard B-complex formulas don't touch.
Adenosylcobalamin, one of two active B12 forms in this formula, has been linked in animal research to maintaining fast-twitch muscle fiber size and neuromuscular junction integrity as those systems age — extending this formula's reach beyond typical B-complex energy claims.
Take 1 capsule, 1-2 times daily, with meals.
No — this is a high-potency, targeted formula. Several B vitamins run well above typical multivitamin amounts, so it's built for mitochondrial and nerve support rather than as a general daily multivitamin replacement.
B vitamins act as coenzymes essential to basal mitochondrial function, and thiamin and niacin specifically support neuron cell longevity and impulse conduction — the same systems that take on added load during high-volume training blocks.