Product Description
You track your macros, dial in your fueling, and time your carbs around training. But if your body isn't efficiently processing the glucose and lipids you're feeding it, you're leaving metabolic performance on the table.
Healthy blood sugar regulation and cardiovascular function aren't just longevity goals — they're the foundation that supports everything from sustained training energy to long-term athletic health.
Pure Encapsulations Berberine UltraSorb delivers 550mg of Berbevis® berberine phytosome — a clinically studied, enhanced-absorption form that's four times more bioavailable than standard berberine supplements.
4x Enhanced Absorption – Standard berberine is notoriously hard for your body to absorb. Berbevis® uses Indena's Phytosome™ technology — bonding berberine to sunflower phospholipids — so more of what you take actually reaches your system. A pharmacokinetic study in healthy adults confirmed this formula delivers four times greater bioavailability than conventional berberine.
AMPK Activation for Metabolic Efficiency – Berberine activates AMPK, often called your body's "metabolic master switch." This enzyme is a central regulator of how your cells produce and use energy — supporting glucose uptake by muscles, healthy insulin signaling, and efficient lipid metabolism. For athletes, that translates to better metabolic flexibility and more stable energy throughout the day.
Cardiometabolic Support for the Long Game – Clinical studies using 1,000–1,500mg of standard berberine daily show support for healthy cholesterol, triglyceride levels, and blood flow. Berberine also supports endothelial function — the health of your blood vessel lining — which matters for every athlete focused on cardiovascular performance and long-term health.
Research supports berberine's role in metabolic health. In a clinical study, berberine supplementation of 500mg twice daily for three months provided significant support for healthy lipid profiles. Multiple randomized, placebo-controlled trials confirm berberine promotes healthy insulin receptor function and glucose metabolism.
How to Use Berberine UltraSorb
Daily Dose: Take 1 capsule, 1–2 times daily, with or between meals.
Timing for Athletes: Because berberine activates AMPK — which can compete with the mTOR pathway involved in muscle building — consider taking it away from your post-workout protein window. Morning or evening dosing works well.
Supplement Facts
60 Servings
Serving Size: 1 capsule
Serving Per Container: 60
| Amount Per Serving | ||
|---|---|---|
| % Daily Value* | ||
| Berbevis® berberine - Indena Phytosome™ complex (Berberine and sunflower phospholipid complex) 550mg | ** | |
* Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.
** Daily Value (DV) not established
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Pure Encapsulations Berberine UltraSorb FAQ's
Everything you need to know before getting started.
Berberine is a natural plant compound found in several herbs, most notably Berberis aristata. It works by activating AMPK — an enzyme that acts as your body's master metabolic switch, helping cells manage energy, blood sugar, and fat metabolism more efficiently. Athletes use it to support stable energy levels, healthy glucose metabolism, and long-term cardiometabolic health — especially during high-carbohydrate training diets.
Take 1 capsule, 1–2 times daily, with or between meals. For athletes, the most effective approach is to take your capsule(s) with your highest-carbohydrate meals of the day — breakfast or post-workout — to support healthy blood sugar management when your glucose load is highest.
Some athletes notice more stable energy and fewer blood sugar swings within the first 1–2 weeks. The deeper metabolic benefits — improved cholesterol, triglyceride, and blood sugar markers — are best assessed after 8–12 weeks of consistent daily use, which aligns with the timeframes used in clinical research on berberine.